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Some people start to feel better almost immediately, but for others, it can take weeks or even months for the body to heal and for the full benefits to kick in

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In the case of aging, it is known that over time, mitochondrial dysfunction occurs in parallel with NAD + depletion in muscle tissues, and often this depletion has been linked to muscle wasting or loss of muscle function 240,241

Older HA filler formulations were bad at that - and so filler wouldnt last very long